A randomized trial of dual-acting bronchodilator AZD8871 for chronic obstructive pulmonary disease

D Singh, R Fuhr, L Jimenez… - American Journal of …, 2019 - atsjournals.org
Long-acting bronchodilators are recommended as maintenance therapy for chronic obstructive
pulmonary disease (COPD… to evaluate its potential as a novel treatment option in COPD. …

Triple therapy versus dual bronchodilation and inhaled corticosteroids/long-acting β-agonists in COPD: accumulating evidence from network meta-analyses

M Cazzola, L Calzetta, P Rogliani, MG Matera - Pulmonary Therapy, 2019 - Springer
… to show that novel treatments are … asthma-COPD overlap (ACO) should be abandoned
because it does not identify a clearly independent disease entity and rather indicates asthmatic

Fixed-dose combinations of long-acting bronchodilators for the management of COPD: global and asian perspectives

CK Rhee, H Yoshisue, R Lad - Advances in Therapy, 2019 - Springer
… for COPD maintenance therapy based on COPDLong-acting bronchodilators (with a
duration of action up to 24 h), such as long-acting muscarinic antagonists (LAMAs) and long-acting

Long-acting muscarinic antagonists under investigational to treat chronic obstructive pulmonary disease

J Ora, A Coppola, M Cazzola, L Calzetta… - Journal of …, 2020 - Taylor & Francis
… antimuscarinic bronchodilator. AZD9164 was the first … program for a novel LAMA to treat
patients with COPD. AZD9164 is … mild persistent asthma and moderate to severe COPD and also …

[HTML][HTML] Impact of long-acting muscarinic antagonists on small airways in asthma and COPD: a systematic review

P Rogliani, BL Ritondo, E Puxeddu, M Cazzola… - Respiratory …, 2021 - Elsevier
… of small airways in COPD and asthma has warranted research … mainstay of COPD treatment
is represented by long-acting β … GLY administered using the novel eFlow® CS nebulizer was …

Relationship of inhaled long-acting bronchodilators with cardiovascular outcomes among patients with stable COPD: a meta-analysis and systematic review of 43 …

C Li, W Cheng, J Guo, W Guan - … Obstructive Pulmonary Disease, 2019 - Taylor & Francis
… a history of asthma, nearly 3 months in acute exacerbation, or had a cardiac complication;
2) the experimental group was a noninhaled long-acting bronchodilator and the intervention …

The novel bronchodilator navafenterol: a phase 2a, multicentre, randomised, double-blind, placebo-controlled crossover trial in COPD

D Singh, J Beier, C Astbury, MG Belvisi… - European …, 2022 - Eur Respiratory Soc
… evidence that long-acting bronchodilators can decrease cough frequency in patients with
COPD, … Characteristics of reversible and nonreversible COPD and asthma and COPD overlap …

[HTML][HTML] Risk of adverse cardiovascular events with use of inhaled long-acting bronchodilators in management of chronic obstructive pulmonary disease

MT Wang, JH Lai, CL Tsai, JT Liou - journal of food and drug analysis, 2019 - Elsevier
… Use of LABAs and LAMAs in patients with COPD, however, … LABAs and LAMAs in management
of COPD, and analyzed the … cardiovascular safety of inhaled long-acting bronchodilators. …

Revefenacin: a once-daily, long-acting bronchodilator for nebulized treatment of COPD

JF Donohue, DA Mahler, S Sethi - … Obstructive Pulmonary Disease, 2019 - Taylor & Francis
… A nebulized ICS (budesonide) is available for the treatment of patients with asthma. Citation52
Other … This novel bronchoselective LAMA offers patients with COPD who require or prefer …

[HTML][HTML] … /glycopyrronium) versus nebulized short-acting dual bronchodilator (salbutamol/ipratropium) in chronic obstructive pulmonary disease: a double-blind …

WH van Geffen, OA Carpaij, LF Westbroek… - Respiratory …, 2020 - Elsevier
… Main exclusion criteria were asthma, chronic hypoxaemia, and the occurrence of a
COPD exacerbation in the six weeks before inclusion. Maintenance concomitant inhaled …